Peptides are made from chains of amino acids, and their size and structure matter. Smaller peptides can be absorbed intact and participate in biological processes, but first they have to make it through the digestive system.
That is where delivery becomes important.
The stomach is highly acidic and contains digestive enzymes designed to break proteins and peptides down. Kura Life uses an enteric-coated delivery system to help protect its bioactive peptide fractions from this environment and delay their release until they reach the small intestine.
Why the small intestine?
Because the small intestine is the body’s primary site of nutrient absorption and provides several established pathways through which appropriately sized peptides can cross the intestinal barrier. Very small peptides, including dipeptides and tripeptides, can be transported through specialized peptide transporters such as PepT1. Other peptides with suitable molecular characteristics may cross between intestinal cells through paracellular transport or through the cells themselves by transcellular transport.
Protecting the peptide fractions until they reach this environment helps preserve the smaller bioactive peptide sequences Kura Life is designed to deliver and allows them to become available for absorption and biological activity.